Prediction of minimal encephalopathy in patients with HCV-related cirrhosis using albumin-bilirubin, platelets-albumin-bilirubin score, albumin-bilirubin-platelets grade and ammonia level

Albumin-bilirubin binding mechanism.

After binding of bilirubin to human serum albumin (1:1), a train of relaxational changes of conformation takes place. The late part of these processes, occurring in the time interval 1-500 s, has been studied by recording the changes of light absorption. Similar processes have been demonstrated after binding of fatty acid anion to the bilirubin-albumin complex as well as after a pH-jump from 6 ...

Serum bilirubin and bilirubin/albumin ratio as predictors of bilirubin encephalopathy.

BACKGROUND AND OBJECTIVE Bilirubin/albumin ratio (B/A) may provide a better estimate of free bilirubin than total serum bilirubin (TSB), thus improving identification of newborns at risk for bilirubin encephalopathy. The objective of the study was to identify thresholds and compare specificities of TSB and B/A in detecting patients with acute and posttreatment auditory and neurologic impairment...

Bilirubin/Albumin Ratio for Predicting Acute Bilirubin-induced Neurologic Dysfunction

OBJECTIVE The aim of this study was to evaluate the bilirubin albumin (B/A) ratio in comparison with total serum bilirubin (TSB) for predicting acute bilirubin-induced neurologic dysfunction (BIND). METHODS Fifty two term and near term neonates requiring phototherapy and exchange transfusion for severe hyperbilirubinemia in Children's Medical Center, Tehran, Iran, during September 2007 to Sep...

Letter: "Albumin-titratable bilirubin" as an index to bilirubin binding.

ogists on the ABA-100, we found that about 13% of the samples (22 of 169) gave results which differed by more than 10 mg/liter. This prompted us to test the assumption concerning the effectiveness of the blanking wavelength. The test wavelength is 650 nm and the blank wavelength is 550 nm for the phosphorus procedure on the ABA-100. We Selected two patients’ samples that had given discrepant re...

Does conjugated bilirubin displace unconjugated bilirubin from albumin.